Seachem Laboratories

Seachem NeoPlex (Broad Spectrum)

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  • Broad spectrum antibiotic effective against most external infections
  • Safe for marine and freshwater
  • Minimal impact on bio-filter


        NeoPlex™ is a broad spectrum antibiotic effective against most external infections of both marine and freshwater fish. Used as directed, NeoPlex™ will not discolor the water or damage the filter bed. It is well tolerated by invertebrates, although delicate species may be stressed.

        Active ingredients: neomycin sulfate (43%) Inactive ingredients: excipients (57%)


        NeoPlex™ is appropriate for treating a variety of external infections of both marine and freshwater fish. Below are some of the more common diseases treatable with NeoPlex™. Be aware that many diseases and infections share similar physical and behavioral symptoms, e.g. clamped fins, lesions, loss of appetite.


        Dosing in Water

        Remove all invertebrates - these are extremely sensitive to medication. Turn off UV filters, ozone filters, and remove chemical filtration like MatrixCarbon™and Purigen®. Use 1 measure (included) per every 8 L (2 US gallons). Repeat this dose every 7 days to a maximum of 3 weeks. This will treat external bacterial infections.

        Dosing in Food

        Feed the medicated food mix every day until the infection clears or up to 1 week. This will treat internal bacterial infections. This medicated food can be refrigerated or frozen between feedings.

        • 1 scoop NeoPlex™
        • 1 scoop Focus™
        • 1 tbsp food (preferably pellets or frozen food)
        • A few drops of water if using a dry food

        To enhance palatability use with GarlicGuard™.

        After Treating

        When the treatment period is over, NeoPlex™ can easily be removed using activated filter carbon like MatrixCarbon™. It does not linger in the substrate or filter media of the tank. Remove with carbon before turning on UV.